OPRM1 interacts_with naltrexone
Evidence from:
primary |
all sources
Evidence (4 sources)
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.
(2023)
PMID:38062264
cited
OPRM1 with naltrexone
confidence: 0.95
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol.
(2012)
PMID:22954510
cited
Interaction with OPMR1 genotype may affect naltrexone response.
confidence: 0.88
A genetic determinant of the striatal dopamine response to alcohol in men.
(2011)
PMID:20479755
cited
presence of the 118G allele was associated with a therapeutic response to the opioid antagonist naltrexone
confidence: 0.85
Consilient research approaches in studying gene x environment interactions in alcohol research.
(2010)
PMID:20148780
cited
interaction between exposure to alcohol and genetic variation in the OPRM1 gene and naltrexone
confidence: 0.92