SNP risk_factor_for schizophrenia
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Evidence (5 sources)
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
(2022)
PMID:35396580
cited
We estimated the cumulative contribution of SNPs to polygenic risk of schizophrenia...
confidence: 0.92
Recent genetic findings in schizophrenia and their therapeutic relevance.
(2015)
PMID:25315827
cited
Both act as risk factors for schizophrenia.
confidence: 0.96
A GRR of 1.15 is large for schizophrenia, and only 10 of 128 SNPs reaching genome‑wide significance had GRR > 1.15.
confidence: 0.92
a large case-control difference suggests an etiological role for a particular SNP ... with disease (schizophrenia).
confidence: 0.95
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
(2009)
PMID:19065143
cited
if the vast majority of genetic risk is conferred almost exclusively by rare alleles
confidence: 0.85