OPRM1 A118G protective_against alcohol dependence
Evidence from:
primary |
all sources
Evidence (2 sources)
One study found the G allele to be protective against alcohol dependence in adult Caucasians.
confidence: 0.80
Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G.
(2014)
PMID:22862850
cited
among alcohol dependent patients treated with naltrexone, those with one or two copies of the G118 allele had better outcome
confidence: 0.92