OPRM1 A118G associated_with morphine
Evidence from:
primary |
all sources
Evidence (2 sources)
G/G individuals requiring more morphine ... to achieve analgesia
confidence: 0.92
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
in patients with acute postoperative and cancer pain, those with the minor allele of OPRM1 require more morphine than those with the major allele
confidence: 0.95