XRCC6 protective_against acetaldehyde

Subject: XRCC6
Relation: protective_against
Object: acetaldehyde
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. (2018) PMID:29323295 cited

Ku70 was required to maintain resistance of short-term (ST) HSCs to aldehydes ... ST-HSCs were much more sensitive to acetaldehyde ... NHEJ is required to provide resistance to endogenous and acetaldehyde-induced DNA damage.

confidence: 0.95