bupropion associated_with abstinence

Subject: bupropion
Relation: associated_with
Object: abstinence
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. (2013) PMID:23249876 cited

Therapy randomization from baseline to EOT was to five different pharmacotherapies [NRT, BUP, PLA, VAR or combined NRT] ... and differ in prevalence of ... 6MO abstinence.

confidence: 0.90

Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. (2012) PMID:22290489 cited

Data from a meta-analysis revealed that bupropion doubles abstinence rates for at least 6 months compared to placebo.

confidence: 0.97

Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation. (2008) PMID:18593715 cited

individuals with the WT genotype and received bupropion had the highest abstinence rates.

confidence: 0.95