brain associated_with PAU

Subject: brain
Relation: associated_with
Object: PAU
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020) PMID:32451486 primary

Functional and heritability analyses consistently showed enrichments in brain regions ... providing biological insights into the etiology of PAU

confidence: 0.96

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. (2023) PMID:38062264 cited

Six brain annotations were used: ... adult brain ... to identify risk genes associated with PAU.

confidence: 0.94