prefrontal cortex associated_with Alcohol Use Disorder

Subject: prefrontal cortex
Relation: associated_with
Object: Alcohol Use Disorder
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder. (2024) PMID:39149227 primary

examined gene expression in nuclei from the prefrontal cortex of individuals with and without AUD... found differences in expression associated with AUD within six cell types

confidence: 0.95

Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits. (2017) PMID:29268093 cited

The PFC is involved in the cognitive symptoms of AUD.

confidence: 0.96