Ucn2 targets CRF2R
Evidence from:
primary |
all sources
Evidence (3 sources)
CRF and the Ucn peptides produce their effects by binding to the G protein-coupled CRF type 1 (CRF1R) and CRF type 2 (CRF2R) receptors.
confidence: 0.93
Stress-related neuropeptides and addictive behaviors: beyond the usual suspects.
(2012)
PMID:23040815
cited
CRF2R selective agonist Ucn2 ... did not replicate the effects of CRF to reinstate cocaine seeking
confidence: 0.90
Stress-related neuropeptides and addictive behaviors: beyond the usual suspects.
(2012)
PMID:23040815
cited
Ucn2 and 3 are highly CRF2R selective
confidence: 0.95