Gabra4 regulates alcohol self-administration

Subject: Gabra4
Relation: regulates
Object: alcohol self-administration
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Alpha4 subunit-containing GABAA receptors in the accumbens shell contribute to the reinforcing effects of alcohol. (2012) PMID:21507158 cited

the GABAAR α4 subunit mediates the reinforcing effects of ethanol

confidence: 0.95

Alpha4 subunit-containing GABAA receptors in the accumbens shell contribute to the reinforcing effects of alcohol. (2012) PMID:21507158 cited

down-regulation of α4 subunits... produces a similar behavioral effect as a general inhibition of GABAARs

confidence: 0.70