pioglitazone targets PPARG

Subject: pioglitazone
Relation: targets
Object: PPARG
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. (2015) PMID:25516156 primary

PPARγ agonist pioglitazone

confidence: 0.98

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014) PMID:24889886 cited

the PPARγ agonist pioglitazone

confidence: 0.90

Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009) PMID:19756185 cited

activation of PPARγ by pioglitazone was shown to reduce the production of TNFα

confidence: 0.95