bipolar disorder associated_with schizophrenia
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Evidence (12 sources)
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
Genome-wide significant loci for BD were assessed for overlap with genome-wide significant loci for ... schizophrenia ...
confidence: 0.96
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
variants that influenced both BD and schizophrenia had high concordance in direction of effect (80%)
confidence: 0.94
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
substantial genetic overlap observed between BD and the other phenotypes
confidence: 0.80
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
Genetic correlation was positive with all psychiatric disorders assessed, particularly schizophrenia (rg = 0.68).
confidence: 0.96
mood and psychotic disorders (MDD, BIP, and SCZ)
confidence: 0.95
15% misdiagnosis rates across bipolar disorder and schizophrenia (Bromet et al., 2011).
confidence: 0.90
Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits.
(2019)
PMID:30962613
cited
large degrees of genetic overlap identified across phenotypes (e.g., bipolar disorder and schizophrenia)
confidence: 0.95
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
(2018)
PMID:29632380
cited
the estimated enrichment correlation between bipolar disorder and schizophrenia was 0.96 (s.e.=0.05)
confidence: 0.95
What Should a Psychiatrist Know About Genetics? Review and Recommendations From the Residency Education Committee of the International Society of Psychiatric Genetics.
(2018)
PMID:30549495
cited
a 70% overlap in common genetic vulnerability markers between bipolar disorder and schizophrenia
confidence: 0.95
Between BPD and SCZ the correlation is 0.68
confidence: 0.96
Genetic and environmental factors in complex neurodevelopmental disorders.
(2007)
PMID:19412416
cited
Bipolar disorder patients show many clinical features that are similar to those of schizophrenic patients
confidence: 0.90
Genetic and environmental factors in complex neurodevelopmental disorders.
(2007)
PMID:19412416
cited
bipolar disorder and schizophrenia may also share a genetic background
confidence: 0.95