childhood conduct disorder risk_factor_for substance use

Subject: childhood conduct disorder
Relation: risk_factor_for
Object: substance use
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Age at first use and later substance use disorder: Shared genetic and environmental pathways for nicotine, alcohol, and cannabis. (2016) PMID:27537477 cited

heritable, trait-level factors that confer vulnerability to substance misuse broadly (e.g., ... childhood externalizing behavior)

confidence: 0.85

Genetic and environmental influences on externalizing behavior and alcohol problems in adolescence: a female twin study. (2009) PMID:19341765 cited

relationship between childhood externalizing ... and substance dependence ... has been well established

confidence: 0.95