hM3Dq interacts_with clozapine-N-oxide
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Evidence (2 sources)
Development of a high-throughput arrayed neural circuitry platform using human induced neurons for drug screening applications.
(2020)
PMID:32064487
cited
hM3Dq ... signals calcium mobilization upon activation by its designer ligand clozapine-N-oxide (CNO).
confidence: 0.94
Development of a high-throughput arrayed neural circuitry platform using human induced neurons for drug screening applications.
(2020)
PMID:32064487
cited
We purposefully chose a receptor that would be present in neurons on only one side of the device in order to measure a purely post-synaptic response... the combination of hM3Dq/CNO.
confidence: 0.96