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AUDIT-C associated_with UKB

Subject
AUDIT-C
Relation
associated_with
Object
UKB
p-value
2e-16
Evidence from: primary | all sources

Evidence (5 sources)

Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. (2022) PMID:33985350 primary
As AUDIT-C and AUDIT-P are computed using an unweighted composite score approach, they inherently rely on the same assumptions.
confidence: 0.85
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020) PMID:32451486 primary
previous associations with AUDIT-C (... 12 genes in UKB)
confidence: 0.90
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
AUDIT-C and AUDIT-P were highly genetically correlated (rg = 0.70, p = 4.1 × 10−70).
confidence: 0.98
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
Genetic analysis ... revealed evidence of distinct genetic architecture between AUDIT-C and AUDIT-P
confidence: 0.95
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019) PMID:30336701 cited
moderate positive phenotypic correlation between AUDIT-C and AUDIT-P (r = 0.478, p < 2 × 10−16)
confidence: 0.98