opioid sensitivity associated_with pain
Evidence from:
primary |
all sources
Evidence (2 sources)
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
Significant individual differences in sensitivity to these drugs can impair effective pain treatment.
confidence: 0.90
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
a significant response was taken to be a 50% reduction in pain, using a 100 mm visual analog scale
confidence: 0.90