OPRM1 A118G biomarker_for naltrexone

Subject: OPRM1 A118G
Relation: biomarker_for
Object: naltrexone
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited

A118G genotype predicts response to naltrexone treatment for alcoholism.

confidence: 0.93

A genetic determinant of the striatal dopamine response to alcohol in men. (2011) PMID:20479755 cited

presence of the 118G allele was associated with a therapeutic response to the opioid antagonist naltrexone

confidence: 0.90