bipolar disorder associated_with major depressive disorder
Evidence from:
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Evidence (7 sources)
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
vast majority of loci influencing BD were also estimated to influence major depression (97%)
confidence: 0.94
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
Genome-wide significant loci for BD were assessed for overlap with genome-wide significant loci for ... major depression ...
confidence: 0.96
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
substantial genetic overlap observed between BD and the other phenotypes
confidence: 0.80
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
Genetic correlation was positive with all psychiatric disorders assessed, particularly ... major depression (rg = 0.44).
confidence: 0.95
Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits.
(2019)
PMID:30962613
cited
joint analysis of GWAS summary statistics from five genetically correlated psychiatric case-control traits: ... bipolar disorder, major depressive disorder (MDD), ...
confidence: 0.96
Between BPD and major depressive disorder, the correlation is 0.47
confidence: 0.95
major depressive disorder and BIP are alike in that both include major depressive episodes
confidence: 0.90