NFKB1 associated_with alcoholism
Evidence from:
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Evidence (4 sources)
Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.
(2007)
PMID:17895971
cited
p50 homodimer DNA binding activity ... were lower in the PFC of alcoholics compared to controls (P = 0.029)
confidence: 0.94
Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.
(2007)
PMID:17895971
cited
p65/p50 protein ratio was significantly decreased ... in the PFC of alcoholics (P = 0.017)
confidence: 0.95
Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.
(2007)
PMID:17895971
cited
Downregulation of DNA-binding of the p50 homodimer and NF-κB in alcoholics...
confidence: 0.90
Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system.
(2007)
PMID:17895971
cited
in alcoholics the p50 homodimer-induced repression ... weakens due to the p50 homodimer downregulation
confidence: 0.85