OPRM1 interacts_with opioid
Evidence from:
primary |
all sources
Evidence (4 sources)
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
Polymorphisms in the genes coding for ... μ‑opioid receptor could partly explain the observed inter‑individual variations in response to opioids.
confidence: 0.80
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
response to opioids
confidence: 0.92
Haplotype block structure of the genomic region of the mu opioid receptor gene.
(2011)
PMID:21160491
cited
OPRM1 ... mediates the effects of opioids.
confidence: 0.85
Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis.
(2009)
PMID:23226031
cited
The mu opioid receptor has a clear involvement in mediating the analgesic and rewarding effects of endogenous and exogenous opioids.
confidence: 0.90