apoE associated_with Alzheimer’s disease
Evidence from:
primary |
all sources
Evidence (5 sources)
Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis: A Simple Solution.
(2023)
PMID:35973856
cited
In line with prior work for ALZ, we also removed the APOE region prior to calculating heritability.
confidence: 0.92
Interpretation of risk loci from genome-wide association studies of Alzheimer's disease.
(2020)
PMID:31986256
cited
replicated the previous association with APOE
confidence: 0.95
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
(2020)
PMID:32341526
cited
the APOE region (chr19:45020859–45844508) for the Alzheimer’s GWAS.
confidence: 0.60
exclude common genetic effects akin to those for APOE and Alzheimer’s disease
confidence: 0.95
replicated associations of Alzheimer’s disease with common variation in APOE
confidence: 0.96