OPRM1 risk_factor_for Alcohol Use Disorder
Evidence from:
primary |
all sources
Evidence (7 sources)
Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol.
(2020)
PMID:32561311
primary
One variant ... in OPRM1 ... associated with AUDs
confidence: 0.85
Differential sensitivity of human neurons carrying μ opioid receptor (MOR) N40D variants in response to ethanol.
(2020)
PMID:32561311
primary
may be involved in the pathogeneses of AUDs
confidence: 0.70
Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents.
(2013)
PMID:23136901
cited
association between a specific functional polymorphism of the µ-opioid receptor (OPRM1) gene, the A118G SNP, and risk for developing an AUD.
confidence: 0.90
Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents.
(2013)
PMID:23136901
cited
examine whether the influence of OPRM1 on alcoholism risk varies depending on specific environmental factors
confidence: 0.94
Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents.
(2013)
PMID:23136901
cited
genotypic risk for an AUD was significantly lower when parental monitoring was higher and significantly heightened when youth affiliated with more deviant peers
confidence: 0.80
Preliminary evidence for a gene-environment interaction in predicting alcohol use disorders in adolescents.
(2013)
PMID:23136901
cited
The candidate gene (OPRM1) was entered as a predictor for AUD diagnosis (presence of alcohol abuse or dependence).
confidence: 0.90
The genetics of alcohol dependence: advancing towards systems-based approaches.
(2012)
PMID:22854292
cited
genetic studies ... highlighted polymorphisms in the genes for opioid receptors (e.g., OPRM1)
confidence: 0.88