Methadone targets OPRM1
Evidence from:
primary |
all sources
Evidence (3 sources)
Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond.
(2022)
PMID:36207451
primary
OPRM1 is a known target of ... OA treatments (e.g., methadone and buprenorphine)
confidence: 0.96
Opioids such as methadone ... are full agonists at the μ-opioid receptor; OPRM1 encodes the μ opioid receptor gene
confidence: 0.94
Methadone acts as a full MOR agonist
confidence: 0.97