pioglitazone protective_against ethanol preference
Evidence from:
primary |
all sources
Evidence (3 sources)
Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans.
(2015)
PMID:25516156
primary
reduced ethanol ... preference after 6 hours; weaker effect after 24 hours
confidence: 0.95
Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans.
(2015)
PMID:25516156
primary
pioglitazone reduced ... ethanol preference (without changing total fluid intake) during the first 6 hours
confidence: 0.96
Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans.
(2015)
PMID:25516156
primary
pioglitazone reduced ethanol preference; effectiveness after 24 h was weaker than at 6 h
confidence: 0.88