rs997917 associated_with sedatives
Evidence from:
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Evidence (3 sources)
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol.
(2012)
PMID:22954510
cited
demonstrating differential naltrexone‑induced changes in alcohol sedation among rs997917 genotype groups
confidence: 0.80
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol.
(2012)
PMID:22954510
cited
OPRK1^2 × medication interaction (β = 0.63, SE = 0.182, t = 3.43, p < .001) showed a significant effect on alcohol-induced sedation.
confidence: 0.96
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol.
(2012)
PMID:22954510
cited
One kappa receptor tSNP (rs997917) ... moderated alcohol-induced sedation
confidence: 0.95