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APP associated_with Alzheimer’s disease

Subject
APP
Relation
associated_with
Object
Alzheimer’s disease
p-value
0.0016
Evidence from: primary | all sources

Evidence (5 sources)

Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. (2018) PMID:30297968 cited
These studies have largely focused on alternative splicing of selected candidate genes, including the amyloid precursor protein (APP)
confidence: 0.60
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. (2018) PMID:30297968 cited
11 genes overlap with the Alzheimer’s disease‑associated splicing in the cortex including APP
confidence: 0.94
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. (2018) PMID:30297968 cited
Other genes ... include APP (P < 1.6 × 10−3; β=−0.003) ... associated with Alzheimer’s disease
confidence: 0.95
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility. (2018) PMID:30297968 cited
11 genes overlap with the Alzheimer’s disease-associated splicing in the cortex including APP
confidence: 0.96
Heritability and genomics of gene expression in peripheral blood. (2014) PMID:24728292 cited
Examples include Alzheimer’s disease (APP and PSEN2)
confidence: 0.96