Crem risk_factor_for drug dependence

Subject: Crem
Relation: risk_factor_for
Object: drug dependence
p-value: 0.02

Evidence from: primary | all sources

Evidence (2 sources)

Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. (2018) PMID:28439100 primary

past drug use was significantly elevated in A-allele carriers with persistent symptomology (t136=2.61, p=0.02)

confidence: 0.92

Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. (2018) PMID:28439100 primary

CREM genotype broadly influences risk for drug dependence, rather than being specific for opiate abuse

confidence: 0.90