NEUROG2 regulates glutamatergic neurons

transient induction of mNgn2 would be sufficient to induce functional excitatory neurons from hiPSC forebrain NPCs

By eliminating the need for sustained overexpression of Ngn2 throughout neuronal induction... produce nearly pure populations of excitatory neurons.

Ngn2-overexpression improves the purity, yield and rate of maturation of excitatory neurons from NPCs

forced expression of Ngn2 ... in postnatal cortical astroglial cells give rise to ... glutamatergic neurons