Dopamine D2 receptor expressed_in nucleus accumbens
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Evidence (5 sources)
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.
(2021)
PMID:34045744
cited
Top genes for each tissue tested were: nucleus accumbens (DRD2, p=1.87×10−20)
confidence: 0.96
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.
(2021)
PMID:34045744
cited
We also find strong support for the importance of DRD2 in the nucleus accumbens.
confidence: 0.95
Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions.
(2021)
PMID:34045744
cited
significant predicted decreased expression in the nucleus accumbens
confidence: 0.90
Association between dopaminergic polymorphisms and borderline personality traits among at-risk young adults and psychiatric inpatients.
(2010)
PMID:20205808
cited
pair bonding ... is partially linked to D2 receptors in nucleus accumbens
confidence: 0.90
NAcc dopamine receptor binding of D2 ... peaks in adolescence
confidence: 0.90