buprenorphine interacts_with benzodiazepines
Evidence from:
primary |
all sources
Evidence (3 sources)
Association Between Benzodiazepine or Z-Drug Prescriptions and Drug-Related Poisonings Among Patients Receiving Buprenorphine Maintenance: A Case-Crossover Analysis.
(2021)
PMID:33653119
primary
Stratification on these variables allowed for observation of possible interaction effects between benzodiazepine dose and buprenorphine use. ... Wald Chi-Square= 4.02, p=0.045
confidence: 0.80
Association Between Benzodiazepine or Z-Drug Prescriptions and Drug-Related Poisonings Among Patients Receiving Buprenorphine Maintenance: A Case-Crossover Analysis.
(2021)
PMID:33653119
primary
individuals taking both buprenorphine and benzodiazepines are at elevated risk of poisoning
confidence: 0.80
Association Between Benzodiazepine or Z-Drug Prescriptions and Drug-Related Poisonings Among Patients Receiving Buprenorphine Maintenance: A Case-Crossover Analysis.
(2021)
PMID:33653119
primary
474,181 person-days entailed concurrent buprenorphine treatment with benzodiazepines or Z drugs
confidence: 0.93