fatty acids regulates PPARα

Subject: fatty acids
Relation: regulates
Object: PPARα
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

CYP2A6 is associated with obesity: studies in human samples and a high fat diet mouse model. (2019) PMID:29568101 primary

Free fatty acids are endogenous ligands to activate PPARα

confidence: 0.95

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. (2016) PMID:26838599 cited

FFA released from adipocytes during fasting influenced hepatic PPARα expression and activity.

confidence: 0.90