cocaine targets prefrontal cortex

Subject: cocaine
Relation: targets
Object: prefrontal cortex
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. (2011) PMID:22011681 cited

main effect of cocaine ... on the PFC is to increase PFC activity

confidence: 0.96

EEG biofeedback as a treatment for substance use disorders: review, rating of efficacy, and recommendations for further research. (2008) PMID:18214670 cited

Cocaine produced a rapid increase in absolute theta, alpha, and beta power over the prefrontal cortex.

confidence: 0.96