OPRM1 risk_factor_for opioid sensitivity
Evidence from:
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Evidence (2 sources)
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
Genetic variability such as polymorphisms in the genes coding for ... μ‑opioid receptor could partly explain the observed inter‑individual variations in response to opioids.
confidence: 0.85
Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.
(2013)
PMID:23402298
cited
minor allele of the OPRM1 gene tended to be associated with increased opioid sensitivity
confidence: 0.90