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CHRNA5 risk_factor_for COPD

Subject
CHRNA5
Relation
risk_factor_for
Object
COPD
p-value
Evidence from: primary | all sources

Evidence (3 sources)

Human Genetics of Addiction: New Insights and Future Directions. (2018) PMID:29504045 cited
CHRNA5 ... influence susceptibility of developing smoking-related health outcomes, including: ... COPD
confidence: 0.94
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. (2011) PMID:21278726 cited
high incidence of ... COPD in individuals carrying CHRNA5 risk alleles
confidence: 0.95
Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25. (2010) PMID:19896728 cited
the α5 nicotinic receptor subunit gene ... as the most likely gene altering the risk for ... COPD.
confidence: 0.90