ADH1B associated_with alcohol metabolism
Evidence from:
primary |
all sources
Evidence (2 sources)
Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk.
(2022)
PMID:36180423
primary
The top SNPs for ALCP-specific are in ADH1B and ADH1C, which are involved in alcohol metabolism.
confidence: 0.96
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
(2021)
PMID:34446935
primary
a missense variant with a well-established role in alcohol metabolism25
confidence: 0.94