morphine risk_factor_for opioid-induced hyperalgesia

Subject: morphine
Relation: risk_factor_for
Object: opioid-induced hyperalgesia
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. (2009) PMID:19214139 cited

spontaneous hyperalgesia observed in humans and mice after chronic exposure to opioids, referred to as OIH

confidence: 0.90

From mouse to man: the 5-HT3 receptor modulates physical dependence on opioid narcotics. (2009) PMID:19214139 cited

protocols for generating opioid-induced hyperalgesia (OIH) ... using morphine

confidence: 0.94