rs75967634 risk_factor_for PAU

Subject: rs75967634
Relation: risk_factor_for
Object: PAU
p-value: 1.07e-09

Evidence from: primary | all sources

Evidence (2 sources)

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020) PMID:32451486 primary

A novel rare ADH1B variant, rs75967634 (p = 1.07 × 10⁻⁹), is genome‑wide significant for PAU.

confidence: 0.98

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. (2023) PMID:38062264 cited

ADH1B*rs75967634 ... identified 100 independent variants ... associated with PAU.

confidence: 0.96