rs2072661 interacts_with bupropion
Evidence from:
primary |
all sources
Evidence (2 sources)
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.
(2008)
PMID:18593715
cited
indication of potential effect modification by bupropion... difference in relapse rates ... for individuals who received bupropion
confidence: 0.80
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.
(2008)
PMID:18593715
cited
the effect of rs2072661 on withdrawal severity was 3.8 units under placebo but only 0.45 units under bupropion, indicating treatment modifies the genetic effect
confidence: 0.80