rare variant risk_factor_for disease

Subject: rare variant
Relation: risk_factor_for
Object: disease
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

A groupwise association test for rare mutations using a weighted sum statistic. (2009) PMID:19214210 cited

multiple rare mutations are expected to influence disease risk

confidence: 0.90

Common and rare variants in multifactorial susceptibility to common diseases. (2008) PMID:18509313 cited

many, if not most, rare variants will have ORs greater than 2, with a significant number considerably greater than 2

confidence: 0.95