OPRM1 A118G associated_with Asian
Evidence from:
primary |
all sources
Evidence (6 sources)
A118G has a minor allele frequency of 38% in Asians
confidence: 0.88
Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPγS binding in mice with Oprm1 A112G.
(2014)
PMID:22862850
cited
A118G allele frequency varies among ethnic groups: 35–49% in Asians...
confidence: 0.93
The 118G allele is common ... Asian ancestry (40–50%).
confidence: 0.95
Haplotype block structure of the genomic region of the mu opioid receptor gene.
(2011)
PMID:21160491
cited
The high prevalence of this allele in the Asian population ... may be explained by genetic drift and/or selective advantage.
confidence: 0.92
Haplotype block structure of the genomic region of the mu opioid receptor gene.
(2011)
PMID:21160491
cited
high frequency in Asian populations (0.35-0.48)
confidence: 0.89
Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis.
(2009)
PMID:23226031
cited
prevalence of the A118G polymorphism is dependent on ethnicity
confidence: 0.90