trans-eQTL associated_with GWAS
Evidence from:
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Evidence (3 sources)
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.
(2021)
PMID:34475573
cited
trans-eQTL ... can be used to interpret GWAS
confidence: 0.90
probability that molecular traits as estimated by cis- and trans-eQTLs and physiological traits as estimated by GWAS share the same causal variant
confidence: 0.95
Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.
(2011)
PMID:21829388
cited
67 (5.7%) SNPs were trans-acting on 130 different transcripts...
confidence: 0.95