CYP2B6 interacts_with nicotine
Evidence from:
primary |
all sources
Evidence (4 sources)
CYP2B6 can also catalyze nicotine metabolism to cotinine and to nornicotine
confidence: 0.90
CYP2B6 has an approximately 10% catalytic efficiency of the CYP2A6 enzyme in vitro in nicotine c-oxidation.
confidence: 0.90
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
association may be mediated by nicotine metabolism rather than bupropion metabolism
confidence: 0.80
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
CYP2B6 may contribute to nicotine metabolism that is not mediated by CYP2A6.
confidence: 0.90