ATM regulates TP53

Subject: ATM
Relation: regulates
Object: TP53
p-value: 3.46e-05

Evidence from: primary | all sources

Evidence (1 sources)

Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. (2015) PMID:26677768 cited

TP53 mRNA was reduced ∼24‑fold in the absence of ATM, and 18 of 19 genes predicted to be transcriptionally regulated by p53 were affected (p = 3.46 × 10⁻5).

confidence: 0.95