paperKB
coga / coga-kb
Help
Sign in

OPRM1 A118G risk_factor_for heavy drinking

Subject
OPRM1 A118G
Relation
risk_factor_for
Object
heavy drinking
p-value
Evidence from: primary | all sources

Evidence (3 sources)

Human Genetics of Addiction: New Insights and Future Directions. (2018) PMID:29504045 cited
rs1799971-A allele conferred increased heroin addiction risk only in the presence of the rs3778150-C allele
confidence: 0.88
Pharmacogenetics of OPRM1. (2014) PMID:24201053 cited
the minor G allele conferred increased risk of addiction ... in the Indian population
confidence: 0.90
Lack of association between the A118G polymorphism of the mu opioid receptor gene (OPRM1) and opioid dependence: A meta-analysis. (2009) PMID:23226031 cited
Studies have identified a significant positive correlation between A118G and heroin addiction
confidence: 0.90