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medium spiny neurons associated_with schizophrenia

Subject
medium spiny neurons
Relation
associated_with
Object
schizophrenia
p-value
0.01
Evidence from: primary | all sources

Evidence (4 sources)

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. (2020) PMID:32341526 cited
the association between schizophrenia and telencephalon projecting inhibitory neurons (i.e. medium spiny neurons) appears to be independent from telencephalon projecting excitatory neurons
confidence: 0.96
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. (2020) PMID:32341526 cited
telencephalon projecting ... inhibitory neurons were strongly associated with schizophrenia ... using both LDSC and MAGMA.
confidence: 0.96
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. (2020) PMID:32341526 cited
found the strongest signals for telencephalon projecting inhibitory neurons (i.e. medium spiny neurons from the striatum) ... associated with schizophrenia
confidence: 0.95
Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. (2020) PMID:32341526 cited
projecting inhibitory neurons (i.e. medium spiny neurons) ... can be prioritized for ... schizophrenia
confidence: 0.95