PAU associated_with major depressive disorder

Subject: PAU
Relation: associated_with
Object: major depressive disorder
p-value: 1.43e-40

Evidence from: primary | all sources

Evidence (2 sources)

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020) PMID:32451486 primary

major depressive disorder (MDD, rg = 0.39, se = 0.03, p = 1.43 × 10−40) showed the highest genetic correlation with PAU

confidence: 0.97

Genetics of substance use disorders in the era of big data. (2021) PMID:34211176 cited

Positive genetic correlations included major depression ...

confidence: 0.90