depression associated_with schizophrenia

Subject: depression
Relation: associated_with
Object: schizophrenia
p-value: 0

Evidence from: primary | all sources

Evidence (8 sources)

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

depression showed significant correlation with ... schizophrenia (rg=0.33, SE=0.021, P=4 x 10−53)

confidence: 0.97

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

MiXeR analyses showing substantial genetic overlap with schizophrenia

confidence: 0.93

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

depression cases who have developed (3) schizophrenia

confidence: 0.95

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

high frequency of depression-cases with a schizophrenia co-diagnosis observed in the iPSYCH sample

confidence: 0.92

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

depression with additional diagnosis of bipolar disorder, schizophrenia or SUD

confidence: 0.90

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

traits showing strong genetic correlation with depression including ... schizophrenia

confidence: 0.96

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses. (2023) PMID:37464041 cited

The additional traits included in the analyses are ADHD..., anxiety..., autism..., bipolar disorder..., educational attainment..., Neuroticism..., schizophrenia..., Smoking Initiation... and substance use disorder...

confidence: 0.90

Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions. (2021) PMID:34045744 cited

shared etiology with schizophrenia ... resulted in substantial loss of GWS SNPs associated with depression when conditioned upon those traits

confidence: 0.95