calcineurin biomarker_for Alzheimer's disease

Subject: calcineurin
Relation: biomarker_for
Object: Alzheimer's disease
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease. (2010) PMID:20590401 cited

Data ... supports prior observations of altered PPP3CA expression in postmortem samples from AD brains.

confidence: 0.86

Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease. (2010) PMID:20590401 cited

Evidence that directly implicates calcineurin in the memory-associated affliction, Alzheimer's disease (AD)

confidence: 0.93