DISC1 risk_factor_for bipolar disorder
Evidence from:
primary |
all sources
Evidence (3 sources)
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
(2014)
PMID:23732877
cited
the translocation that disrupts DISC1 ... associated with diagnoses of SZ, BP and rMDD.
confidence: 0.85
708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.
(2014)
PMID:23732877
cited
Case–control association was tested ... individually for BP ... using Fisher's exact test.
confidence: 0.90
Genetic and environmental factors in complex neurodevelopmental disorders.
(2007)
PMID:19412416
cited
susceptibility genes for schizophrenia have been reported to associate with bipolar disorder as well, including DISC1
confidence: 0.90