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major depressive disorder associated_with cocaine

Subject
major depressive disorder
Relation
associated_with
Object
cocaine
p-value
Evidence from: primary | all sources

Evidence (2 sources)

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. (2011) PMID:22011681 cited
criteria for major depressive disorder ... are met by many drug-addicted individuals (for example, 50% of cocaine-addicted individuals)
confidence: 0.85
Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals. (2009) PMID:18775607 cited
MDD and PTSD were associated with an increased likelihood of cocaine dependence treatment or self-help participation
confidence: 0.96